BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix.

@article{Badr2008BDPC,
  title={BD ProEx C: a sensitive and specific marker of HPV-associated squamous lesions of the cervix.},
  author={Riem E Badr and Ann E Walts and Franca Chung and Shikha Bose},
  journal={The American journal of surgical pathology},
  year={2008},
  volume={32 6},
  pages={
          899-906
        }
}
BD ProEx C (ProEx C) is a recently developed immunocytochemical assay that targets the expression of topoisomerase II-alpha and minichromosome maintenance protein-2, 2 genes shown to be overexpressed in cervical cancers. Recent studies validated this reagent in liquid-based cytology specimens and suggested its usefulness as an adjunct in the diagnosis of challenging cases. Limited information is available on its expression in tissue sections. This study aims to assess ProEx C expression… CONTINUE READING
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