BCG in the treatment of acute lymphocytic leukemia.

@article{Heyn1975BCGIT,
  title={BCG in the treatment of acute lymphocytic leukemia.},
  author={Ruth Heyn and Pal Joo and Myron Karon and Mark Nesbit and N D Shore and Norman Breslow and John Weiner and Ann Reed and Denman Hammond},
  journal={Blood},
  year={1975},
  volume={46 3},
  pages={431-42}
}
Children with acute lymphocytic leukemia, who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate, were randomized into three groups receiving (1) no further therapy, (2) BCG, and (3) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine. Children continuing in remission after 8 mo on chemotherapy in group 3 were rerandomized into three similar groups, i.e., no therapy, BCG, and chemotherapy. In the primary… CONTINUE READING

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Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
Children with acute lymphocytic leukemia , who were in remission after induction with prednisone and vincristine and consolidation with intravenous methotrexate , were randomized into three groups receiving ( 1 ) no further therapy , ( 2 ) BCG , and ( 3 ) chemotherapy with biweekly methotrexate and monthly prednisone and vincristine .
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