BC 1-FMRP interaction is modulated by 2 0-O-methylation : RNA-binding activity of the tudor domain and translational regulation at synapses

@inproceedings{Lacoux2012BC1I,
  title={BC 1-FMRP interaction is modulated by 2 0-O-methylation : RNA-binding activity of the tudor domain and translational regulation at synapses},
  author={Caroline Lacoux and Daniele Di Marino and Pietro Pilo Boyl and Francesca Zalfa and Bing Yan and Maria Teresa Ciotti and Mattia Falconi and Henning Urlaub and Tilmann Achsel and Annie Mougin and Mich{\`e}le Caizergues-Ferrer and Claudia Bagni},
  year={2012}
}
The brain cytoplasmic RNA, BC1, is a small non-coding RNA that is found in different RNP particles, some of which are involved in translational control. One component of BC1-containing RNP complexes is the fragile X mental retardation protein (FMRP) that is implicated in translational repression. Peptide mapping and computational simulations show that the… CONTINUE READING