BASiCS: Bayesian Analysis of Single-Cell Sequencing Data

Abstract

Single-cell mRNA sequencing can uncover novel cell-to-cell heterogeneity in gene expression levels in seemingly homogeneous populations of cells. However, these experiments are prone to high levels of unexplained technical noise, creating new challenges for identifying genes that show genuine heterogeneous expression within the population of cells under… (More)
DOI: 10.1371/journal.pcbi.1004333

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