BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons.

@article{Ding2009BARHL2DR,
  title={BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons.},
  author={Qian Chang Ding and Hui Chen and Xiaoling Xie and Richard T Libby and Ning Tian and Lin Gan},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 13},
  pages={
          3992-4003
        }
}
Through transcriptional regulations, the BarH family of homeodomain proteins play essential roles in cell fate specification, cell differentiation, migration, and survival. Barhl2, a member of the Barh gene family, is expressed in retinal ganglion cells (RGCs), amacrine cells (ACs), and horizontal cells. Here, to investigate the role of Barhl2 in retinal development, Barhl2-deficient mice were generated. Analysis of AC subtypes in Barhl2-deficient retinas suggests that Barhl2 plays a critical… CONTINUE READING
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