BALB/c 3T3 cell transformation assay for the prediction of carcinogenic potential of chemicals and environmental mixtures.

@article{Mascolo2010BALBc3C,
  title={BALB/c 3T3 cell transformation assay for the prediction of carcinogenic potential of chemicals and environmental mixtures.},
  author={Maria Grazia Mascolo and Stefania Perdichizzi and Francesca Rotondo and Elena Morandi and Angela Guerrini and Paola Silingardi and Monica Vaccari and Sandro Grilli and Annamaria Colacci},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2010},
  volume={24 4},
  pages={1292-300}
}
The prediction of the carcinogenic risk for humans is mostly based on animal experiments. For the last 20 years, however, the scientific community has paid great attention to alternative strategies in compliance with common moral and ethical values. The new European chemical regulation REACH (Reg. EC 1907/2006) requires the performance of new studies in… CONTINUE READING