BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.

@article{Aguiar2000BALIA,
  title={BAL is a novel risk-related gene in diffuse large B-cell lymphomas that enhances cellular migration.},
  author={Ricardo Aguiar and Yoshihiro Yakushijin and Samir Kharbanda and Ravi Salgia and Jonathan Alfred Fletcher and Margaret A Shipp},
  journal={Blood},
  year={2000},
  volume={96 13},
  pages={4328-34}
}
Clinical risk factor models such as the International Prognostic Index are used to identify diffuse large B-cell lymphoma (DLB-CL) patients with different risks of death from their diseases. To elucidate the molecular bases for these observed clinical differences in outcome, differential display was used to identify a novel gene, termed BAL (B-aggressive lymphoma), which is expressed at significantly higher levels in fatal high-risk DLB-CLs than in cured low-risk tumors. The major BAL… CONTINUE READING

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