B7-H3 and Its Role in Antitumor Immunity

@inproceedings{Loos2010B7H3AI,
  title={B7-H3 and Its Role in Antitumor Immunity},
  author={Martin J Loos and Dennis M. Hedderich and Helmut Friess and Joerg Kleeff},
  booktitle={Clinical & developmental immunology},
  year={2010}
}
B7-H3 is one of the most recently identified members of the B7/CD28 superfamily of costimulatory molecules serving as an accessory modulator of T-cell response. Recently, B7-H3 expression has been reported in several human cancers indicating an additional function of B7-H3 as a regulator of antitumor immunity. However, its precise physiologic role is still elusive, because both stimulatory and inhibitory capacities have been demonstrated. This paper summarizes the available data on B7-H3 in the… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 40 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 57 references

Similar Papers

Loading similar papers…