B vitamins increase the analgesic effect of ketorolac in the formalin test in the rat.

@article{MedinaSantilln2004BVI,
  title={B vitamins increase the analgesic effect of ketorolac in the formalin test in the rat.},
  author={Roberto Medina-Santill{\'a}n and Gerardo Reyes-Garc{\'i}a and H{\'e}ctor Isaac Rocha-Gonz{\'a}lez and Vinicio Granados-Soto},
  journal={Proceedings of the Western Pharmacology Society},
  year={2004},
  volume={47},
  pages={95-9}
}
The purpose of this study was to assess the possible synergistic interaction between ketorolac and B-vitamins in the rat formalin test. Female Wistar rats were injected into the dorsal surface of the right hind paw with 50 microl of diluted formalin (1%). Reduction of number of flinches was considered as antinociception. Ketorolac (0.32-10 mg/kg, po), B… CONTINUE READING