B vitamins and magnetic resonance imaging-detected ischemic brain lesions in patients with recent transient ischemic attack or stroke: the VITAmins TO Prevent Stroke (VITATOPS) MRI-substudy.

Abstract

BACKGROUND AND PURPOSE Elevated concentrations of homocysteine are associated with cerebral small vessel disease (CSVD). B-vitamin supplementation with folate and vitamins B12 and B6 reduces homocysteine concentrations. In a substudy of the VITAmins TO Prevent Stroke (VITATOPS) trial, we assessed the hypothesis that the addition of once-daily supplements of… (More)
DOI: 10.1161/STROKEAHA.112.665703

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@article{Cavalieri2012BVA, title={B vitamins and magnetic resonance imaging-detected ischemic brain lesions in patients with recent transient ischemic attack or stroke: the VITAmins TO Prevent Stroke (VITATOPS) MRI-substudy.}, author={Margherita Cavalieri and Reinhold Schmidt and Christopher Chen and Vincent Mok and Gabriel Rodr{\'i}guez de Freitas and Swithin J Song and Qilong Yi and Stefan Ropele and Anja Grazer and Nina Homayoon and Christian Enzinger and Katherine Loh and Ka Sing Wong and Adrian Wong and Yunyun Xiong and Hui Chang and Meng Cheong Wong and Franz Fazekas and John W. Eikelboom and Graeme J. Hankey}, journal={Stroke}, year={2012}, volume={43 12}, pages={3266-70} }