B lymphocytes participate in cross-presentation of antigen following gene gun vaccination.

@article{Hon2005BLP,
  title={B lymphocytes participate in cross-presentation of antigen following gene gun vaccination.},
  author={Huiming Hon and Alp Oran and Thomas Brocker and Joshy Jacob},
  journal={Journal of immunology},
  year={2005},
  volume={174 9},
  pages={
          5233-42
        }
}
Although endocytosed proteins are commonly presented via the class II MHC pathway to stimulate CD4(+) T cells, professional APCs can also cross-present Ags, whereby these exogenous peptides can be complexed with class I MHC for cross-priming of CD8(+) T cells. Whereas the ability of dendritic cells (DCs) to cross-present Ags is well documented, it is not known whether other APCs may also play a role, or what is the relative contribution of cross-priming to the induction of acquired immunity… CONTINUE READING

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