B-lymphocytes are predominantly involved in viral propagation of hepatitis C virus (HCV).

@article{Mueller1994BlymphocytesAP,
  title={B-lymphocytes are predominantly involved in viral propagation of hepatitis C virus (HCV).},
  author={Helena M Mueller and Birgit Kallinowski and Christine Solbach and Lorenz Theilmann and Tobias Goeser and Eberhard Pfaff},
  journal={Archives of virology. Supplementum},
  year={1994},
  volume={9},
  pages={307-16}
}
Recent reports have shown that HCV infection is not only restricted to hepatocytes. Like hepatitis B virus (HBV), which also was thought to be strictly hepatotropic in early molecular and cellular investigations, infection of lymphoid cells by HCV in vivo has been demonstrated. We showed that total peripheral blood leukocytes of chronically HCV-infected patients are infected by detection of plus- and minus-stranded HCV RNA using strand-specific oligonucleotide primers in the RT-PCR. These cells… CONTINUE READING
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