B lymphocyte colony formation in vitro: ultrastructural development of individual colonies.

@article{Poulsen1980BLC,
  title={B lymphocyte colony formation in vitro: ultrastructural development of individual colonies.},
  author={P B Poulsen and Mogens Helweg Cla{\"e}sson},
  journal={Differentiation; research in biological diversity},
  year={1980},
  volume={17 2},
  pages={77-84}
}
B lymphocyte colony development in agar culture was studied using an electron microscope, and more than 3,000 colony cells were identified and photographed. In early cultures (day 4) lymphoblasts dominated the colonies. From day 5 onwards plasmablasts and small lymphocytes were present in colonies. From day 6 onward mature plasma cells were observed in… CONTINUE READING