B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis.

Abstract

B lymphocyte autoimmunity plays a crucial role in the pathogenesis of rheumatoid arthritis. The local production of autoantibodies and the presence of ectopic lymphoid neogenesis in the rheumatoid synovium suggest that these dedicated microenvironments resembling canonical lymphoid follicles may regulate the initiation and maturation of B cell autoimmunity… (More)

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@article{Cantaert2008BLA, title={B lymphocyte autoimmunity in rheumatoid synovitis is independent of ectopic lymphoid neogenesis.}, author={Tineke Cantaert and Johanna Kolln and Trieneke C G Timmer and Tineke C. T. M. van der Pouw Kraan and Bernard Vandooren and Rogier M. Thurlings and Juan D. Ca{\~n}ete and A Anca Irinel Catrina and Theo A. Out and Cor L. Verweij and Yiping Zhang and Paul Peter Tak and D. Baeten}, journal={Journal of immunology}, year={2008}, volume={181 1}, pages={785-94} }