B lymphocyte antigen receptor signaling: initiation, amplification, and regulation

@inproceedings{Packard2013BLA,
  title={B lymphocyte antigen receptor signaling: initiation, amplification, and regulation},
  author={Thomas A Packard and John C Cambier},
  booktitle={F1000prime reports},
  year={2013}
}
B lymphocytes and their differentiated daughters are charged with responding to the myriad pathogens in our environment and production of protective antibodies. A sample of the protective antibody produced by each clone is utilized as a component of the cell's antigen receptor (BCR). Transmembrane signals generated upon antigen binding to this receptor provide the primary directive for the cell's subsequent response. In this report, we discuss recent progress and current controversy regarding B… CONTINUE READING