B-lineage lymphoid blast crisis in juvenile chronic myelogenous leukemia: II. Interleukin-1-mediated autocrine growth regulation of the lymphoblasts.

@article{Attias1995BlineageLB,
  title={B-lineage lymphoid blast crisis in juvenile chronic myelogenous leukemia: II. Interleukin-1-mediated autocrine growth regulation of the lymphoblasts.},
  author={Dina Attias and Thomas Grunberger and Wilma Vanek and Zeev Estrov and Amos Cohen and Raymond Lau and Melvin H. Freedman},
  journal={Leukemia},
  year={1995},
  volume={9 5},
  pages={884-8}
}
A pre-B acute lymphoblastic leukemia (ALL) cell line with monosomy 7 was established from a child with juvenile chronic myelogenous leukemia (JCML) in lymphoid blast crisis. Analysis of the growth properties of the cell line, termed 'W1' showed an interleukin-1 (IL-1) mediated autocrine pattern of cell proliferation with the following features: W1 colony… CONTINUE READING