B-haplotype influence on Marek's disease, Rous sarcoma, and lymphoid leukosis virus-induced tumors in chickens.

@article{Bacon1981BhaplotypeIO,
  title={B-haplotype influence on Marek's disease, Rous sarcoma, and lymphoid leukosis virus-induced tumors in chickens.},
  author={Larry D. Bacon and Richard L. Witter and Lyman B. Crittenden and Aly M. Fadly and J F Motta},
  journal={Poultry science},
  year={1981},
  volume={60 6},
  pages={1132-9}
}
Experiments were conducted to establish whether B-haplotype genes that determine resistance to RSV-induced tumors would also influence resistance to Marek's disease and lymphoid leukosis. Matings of line 6(3) x 15(1) F3 or F4 breeders segregating for the Ea-B locus antigens that are markers for B2 and B5 haplotypes of the B major histocompatibility complex were made to produce B2B2, B2B5, and B5B5 chicks. The chicks were infected with a standard inoculum of one of the three tumor viruses in… CONTINUE READING

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