B-chronic lymphocytic leukemia: practical aspects.

@article{Pangalis2002BchronicLL,
  title={B-chronic lymphocytic leukemia: practical aspects.},
  author={Gerassimos Alexander Pangalis and Theodoros Vassilakopoulos and Maria N Dimopoulou and Marina P. Siakantaris and Flora N. Kontopidou and Maria K Angelopoulou},
  journal={Hematological oncology},
  year={2002},
  volume={20 3},
  pages={103-46}
}
B-CLL is the most common adult leukemia in the Western world. It is a neoplasia of mature looking B-monoclonal lymphocytes co-expressing the CD5 antigen (involving the blood, the bone marrow, the lymph nodes and related organs). Much new information about the nature of the neoplastic cells, including chromosomal and molecular changes as well as mechanisms participating in the survival of the leukemic clone have been published recently, in an attempt to elucidate the biology of the disease and… CONTINUE READING
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