B cells undergo unique compartmentalized redistribution in multiple sclerosis.

  title={B cells undergo unique compartmentalized redistribution in multiple sclerosis.},
  author={Juergen Haas and Isabelle Bekeredjian-Ding and Miriam Milkova and Bettina Balint and Alexander Schwarz and Mirjam Korporal and Sven Jarius and Brigitte Fritz and H. G. Lorenz and Brigitte T. Wildemann},
  journal={Journal of autoimmunity},
  volume={37 4},
Increasing evidence fosters the role of B cells (BC) in multiple sclerosis (MS). The compartmentalized distribution of BC in blood and cerebrospinal fluid (CSF) is incompletely understood. In this study, we analyzed BC-patterns and BC-immunoreactivity at these sites during active and during stable disease and the impact of disease modifying drugs (DMD) on peripheral BC-homeostasis. For this purpose we assessed BC-subsets in blood and CSF from patients with clinically isolated syndrome (CIS… CONTINUE READING
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