B cells turn off virgin but not memory T cells.
@article{Fuchs1992BCT, title={B cells turn off virgin but not memory T cells.}, author={Ephraim Joseph Fuchs and Polly Matzinger}, journal={Science}, year={1992}, volume={258 5085}, pages={ 1156-9 } }
There are three possible outcomes when a T cell recognizes a cell bearing a self or foreign antigen. (i) The T cell is not sufficiently signaled and is unaffected. (ii) The T cell is activated. (iii) The T cell is turned off. The differentiation state of the T cell is critical to the outcome. Although both virgin and memory T cells can be activated by antigens presented by "professional" antigen-presenting cells such as dendritic cells, they differ in their responses to B cells. Experienced T…
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