B cell superantigens in HIV-1 infection.

@article{Mueller1997BCS,
  title={B cell superantigens in HIV-1 infection.},
  author={S L Mueller and H K{\"o}hler},
  journal={International reviews of immunology},
  year={1997},
  volume={14 4},
  pages={
          339-49
        }
}
HIV-I infection affects many of the cellular components vital for the maintenance of immune homeostasis. Similar to the T cell superantigen effect on T cell expansion and depletion in AIDS. HIV components with B cell superantigenic properties could be responsible for the observed B cell activation and skewing of VH family usage. Current data on possible B cell superantigen properties of HIV proteins (gp120) are mostly based on studies describing the clonality and VH family usage of… CONTINUE READING

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