B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes.

@article{Takai1988BCS,
  title={B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes.},
  author={Yoshimi Takai and Gordon G. Wong and Steven C. Clark and S J Burakoff and Steven H Herrmann},
  journal={Journal of immunology},
  year={1988},
  volume={140 2},
  pages={508-12}
}
The induction of cytotoxic T lymphocytes (CTL) from precursor T cells requires both antigen and lymphokine signals. Previous work from our laboratory has indicated that three lymphokines are required for the induction of CTL from murine thymocytes; interleukin 2, interferon-gamma (IFN-gamma), and a partially characterized factor referred to as cytotoxic differentiation factor (CDF). While attempting to clone CDF from the human T cell line C10-MJ2, we found that a gene encoding CDF-like activity… CONTINUE READING