B cell malignant lymphoma in a patient with progressive systemic sclerosis and Sjögren's syndrome. Report of a case and review of the literature.

Abstract

We report a patient with progressive systemic sclerosis (PSS) and Sjogren's syndrome (SS) who developed B cell malignant lymphoma 11 and 10 years after the onset of signs of PSS and SS, respectively. As her lymphoma developed, autoantibodies such as rheumatoid factor and antinuclear antibody disappeared from the serum, the lupus erythematosus test yielded negative results and her immunoglobulin levels declined. A good response to chemotherapy was obtained but she died of acute interstitial pneumonitis. Postmortem examination revealed marked diffuse interstitial fibrosis of the lungs.

Cite this paper

@article{Sugai1985BCM, title={B cell malignant lymphoma in a patient with progressive systemic sclerosis and Sj{\"{o}gren's syndrome. Report of a case and review of the literature.}, author={Susumu Sugai and Tomoo Takiguchi and Yuki Hirose and Satoshi Shimizu and Jun Tachibana and Susumu Konda and Fumio Konishi}, journal={Japanese journal of medicine}, year={1985}, volume={24 2}, pages={155-63} }