B cell differentiation induced by lipopolysaccharide. IV. Development of immunoglobulin class restriction in precursors of IgG-synthesizing cells.

Abstract

Direct immunofluorescence was used to determine the classes of immunoglobulins expressed on the surface membrane and in the cytoplasm of newborn and adult B lymphocytes differentiating in response to LPS in vitro. In both newborn and adult spleen, a small proportion of IgM-bearing B lymphocytes also stained for IgG2; adult spleen contained an additional… (More)

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@article{Kearney1976BCD, title={B cell differentiation induced by lipopolysaccharide. IV. Development of immunoglobulin class restriction in precursors of IgG-synthesizing cells.}, author={Joseph F. Kearney and M. D. Cooper and A. R. Lawton}, journal={Journal of immunology}, year={1976}, volume={117 5 Pt 1}, pages={1567-72} }