B cell and immunoglobulin heterogeneity in carp (Cyprinus carpio L.); an immuno(cyto)chemical study.

@article{Diepen1995BCA,
  title={B cell and immunoglobulin heterogeneity in carp (Cyprinus carpio L.); an immuno(cyto)chemical study.},
  author={J C Koumans-van Diepen and Egbert Egberts and Bernardo R. Peixoto and Nicolaas Jacobus Maria Taverne and Jan H.W.M. Rombout},
  journal={Developmental and comparative immunology},
  year={1995},
  volume={19 1},
  pages={
          97-108
        }
}
B cell and immunoglobulin (Ig) heterogeneity was demonstrated in carp, Cyprinus carpio L., using two monoclonal antibodies (MAbs; WC14, WCI12) produced against carp serum Ig. Immunochemical results showed that both WCI4 and WCI12 react with a protein determinant on the heavy chain of Ig (relative molecular mass approximately 70,000). Immunofluorescence microscopic and flow cytometric analyses of lymphoid cells suggest three distinct subpopulations of B cells and plasma cells: WCI4+12- cells… CONTINUE READING

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