B-cell activation in cats with feline infectious peritonitis (FIP) by FIP-virus-induced B-cell differentiation/survival factors

@article{Takano2008BcellAI,
  title={B-cell activation in cats with feline infectious peritonitis (FIP) by FIP-virus-induced B-cell differentiation/survival factors},
  author={Tomomi Takano and Natsuko Azuma and Yoshikiyo Hashida and Ryoichi Satoh and Tsutomu Hohdatsu},
  journal={Archives of Virology},
  year={2008},
  volume={154},
  pages={27-35}
}
It has been suggested that antibody overproduction plays a role in the pathogenesis of feline infectious peritonitis (FIP). However, only a few studies on the B-cell activation mechanism after FIP virus (FIPV) infection have been reported. The present study shows that: (1) the ratio of peripheral blood sIg+ CD21− B-cells was higher in cats with FIP than in SPF cats, (2) the albumin-to-globulin ratio has negative correlation with the ratio of peripheral blood sIg+ CD21− B-cell, (3) cells… CONTINUE READING
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