B and T lymphocyte attenuator regulates T cell survival in the lung.

@article{Deppong2008BAT,
  title={B and T lymphocyte attenuator regulates T cell survival in the lung.},
  author={Christine M. Deppong and Jessica M Degnan and Theresa L. Murphy and Kenneth M Murphy and Jonathan Green},
  journal={Journal of immunology},
  year={2008},
  volume={181 5},
  pages={2973-9}
}
The initiation, intensity, and duration of T cell-directed inflammatory responses are dependent upon the coordination of both activating and inhibitory signals mediated by specific receptors on the T lymphocyte. The recently described receptor, B and T lymphocyte attenuator (BTLA), has been demonstrated to have an important role in limiting the duration of inflammation in a murine model of allergic asthma. In this study, we have examined the role of BTLA on the proliferation, recruitment, and… CONTINUE READING
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