B Lymphocyte Stimulator ( BLyS ) Overexpression in Patients with Systemic Lupus Erythematosus

@inproceedings{Bahgat2013BLS,
  title={B Lymphocyte Stimulator ( BLyS ) Overexpression in Patients with Systemic Lupus Erythematosus},
  author={Dina M Rasheed Bahgat and Rasha El-Sayed Gheith and Olfat T Shaker},
  year={2013}
}
Members of the tumour necrosis factor (TNF) family induce pleiotropic biological responses, including cell growth, differentiation and even death. B lymphocyte stimulator (BLyS), a member of the tumour necrosis factor (TNF) superfamily, is a cytokine that induces B-cell survival, expansion, and differentiation both in vitro and in vivo. Considerable evidence points to a role for (BLyS) overproduction in murine and human Systemic Lupus Erythematosus (SLE). Increased levels of BLyS mRNA… CONTINUE READING

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