Azithromycin fails to reduce inflammation in cystic fibrosis airway epithelial cells.

@article{SaintCriq2012AzithromycinFT,
  title={Azithromycin fails to reduce inflammation in cystic fibrosis airway epithelial cells.},
  author={Vinciane Saint-Criq and Manon Ruffin and Carine Rebeyrol and Lo{\"i}c Guillot and J. -P. Jacquot and Annick Cl{\'e}ment and Olivier Tabary},
  journal={European journal of pharmacology},
  year={2012},
  volume={674 1},
  pages={1-6}
}
Cystic fibrosis is a hereditary disease caused by a mutation in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene that encodes a chloride (Cl(-)) channel. Cystic fibrosis pulmonary pathophysiology is characterised by chronic inflammation and bacterial infections. Azithromycin, a macrolide antibiotic, has shown promising anti-inflammatory properties in some inflammatory pulmonary diseases. Moreover, all clinical studies have presented an improvement of the respiratory condition… CONTINUE READING
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