Azithromycin as an adjunctive treatment of generalized severe chronic periodontitis: clinical, microbiologic, and biochemical parameters.

@article{Han2012AzithromycinAA,
  title={Azithromycin as an adjunctive treatment of generalized severe chronic periodontitis: clinical, microbiologic, and biochemical parameters.},
  author={Buket Han and G{\"u}lnur Emingil and G{\"u}ven {\"O}zdemir and Taina I Tervahartiala and Caner Vural and G Ekin Atilla and Haluk Baylas and Timo Sorsa},
  journal={Journal of periodontology},
  year={2012},
  volume={83 12},
  pages={1480-91}
}
BACKGROUND This study examines the efficacy of azithromycin in combination with non-surgical periodontal therapy on clinical and microbiologic parameters and gingival crevicular fluid (GCF) matrix metalloproteinases-8 (MMP-8) levels over 6 months in patients with severe generalized chronic periodontitis (CP). METHODS Twenty-eight of 36 patients with severe generalized CP were included in this randomized, double-masked, placebo-controlled, parallel-arm study. They were randomly assigned to… CONTINUE READING