Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.

@article{kerblom1985AzidocytidineIA,
  title={Azidocytidine is a specific inhibitor of deoxyribonucleotide synthesis in 3T6 cells.},
  author={Lennart {\AA}kerblom and Peter Reichard},
  journal={The Journal of biological chemistry},
  year={1985},
  volume={260 16},
  pages={
          9197-202
        }
}
2'-Azidocytidine is a specific inhibitor of DNA synthesis in cultured 3T6 mouse fibroblasts. Earlier work (Akerblom, L., Pontis, E., and Reichard, P. (1982) 257, 6776-6782) indicated that the nucleoside, after phosphorylation, acted by inhibiting both ribonucleotide reduction and DNA strand elongation. We now demonstrate that the effect on strand elongation was due to a contamination of azidocytidine with less than 0.3% of arabinosyl cytosine. Pure azidocytidine inhibits specifically… CONTINUE READING