Azelaic Acid: Properties and Mode of Action

  title={Azelaic Acid: Properties and Mode of Action},
  author={Martin A. Sieber and Johannes Kolja Hegel},
  journal={Skin Pharmacology and Physiology},
  pages={9 - 17}
Acne is a common skin disorder that can be problematic for adults as well as for adolescents. It has several key pathophysiological features such as follicular hyperkeratosis, elevated Propionibacterium acnes proliferation, and reactive inflammation, all of which should be targeted for an optimal outcome. Azelaic acid (AzA) has profound anti-inflammatory, antioxidative effects, and is bactericidal against a range of Gram-negative and Gram-positive microorganisms as well, including antibiotic… 

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