Azathioprine and prednisone combination therapy in refractory coeliac disease

@article{Goerres2003AzathioprineAP,
  title={Azathioprine and prednisone combination therapy in refractory coeliac disease},
  author={Marije S. Goerres and Jos W. R. Meijer and P. J. Wahab and J A M Kerckhaert and Patricia J.T.A. Groenen and J Han van Krieken and Chris J. Mulder},
  journal={Alimentary Pharmacology \& Therapeutics},
  year={2003},
  volume={18}
}
Introduction:  Refractory coeliac disease (RCD) is a rare syndrome with a poor prognosis, defined by malabsorption due to gluten‐related enteropathy after initial or subsequent failure of a strict gluten‐free diet and after exclusion of any disorder mimicking coeliac disease. 
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193 Citations
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193 Citations

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Citation Type

Tioguanine in the treatment of refractory coeliac disease – a single centre experience
TLDR
Tioguanine (TG) might be better tolerated and more efficacious owing to a simpler metabolism towards bioactivation than corticosteroids in refractory coeliac disease type I.
Complete Resolution of Type 1 Refractory Celiac Disease after Combined Treatment with Budesonide and Azathioprine: A Case Report and Literature Review
TLDR
The case of a 54 year-old man with refractory celiac disease is presented who required treatment with both budesonide and azathioprine and a concise review of the clinical Management of Refractory Celiac Disease is performed.
Refractory Celiac Disease.
TLDR
Refractory celiac disease has been subdivided into 2 subgroups according to the normal (RCDI) or abnormal phenotype of intraepithelial lymphocytes (IELs) (RCDII) and RCDII, which is considered as a low-grade intraepIThelial lymphoma and has a poor prognosis.
Refractory Celiac Disease Successfully Treated With Azathioprine
Refractory celiac disease (CD) is a clinical diagnosis defined by the persistence of signs/symptoms, laboratory abnormalities or villous atrophy typical of CD despite strict adherence to a…
Refractory celiac disease
TLDR
Different types of refractory celiac disease are described and diagnostic and therapeutic guidelines for its clinical management are proposed.
Refractory celiac disease.
TLDR
The clinical and pathologic features of RCD and recent pathogenic findings in RCDII are reviewed, offering a model to study how inflammation can drive T-cell lymphomagenesis.
Update on the Diagnosis and Management of Refractory Coeliac Disease
TLDR
The clinical characteristics of RCDI and RCDII, diagnostic approach, and the latest insights in treatment options are described.
Refractory coeliac disease
TLDR
The distinctive diagnostic features of RCDI and RCDII, the risk of developing overt lymphoma and different therapeutic approaches are reviewed.
Editorial: Is Refractory Celiac Disease More Severe in Old Europe?
TLDR
The diagnostic criteria of RCDI and RCDII, and the possible factors underlying the more severe expression of celiac disease in Europe, are discussed.
Management of Patients with Refractory Coeliac Disease
TLDR
Subjects with RCD carry a high risk of complications, including ulcerative jejunitis and lymphoma affecting the small intestine, the latter termed enteropathy-associated T-cell lymphoma (EATL).
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References

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TLDR
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TLDR
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TLDR
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TLDR
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