Azathioprine and interferon beta(1a) in relapsing-remitting multiple sclerosis patients: increasing efficacy of combined treatment.

@article{Lus2004AzathioprineAI,
  title={Azathioprine and interferon beta(1a) in relapsing-remitting multiple sclerosis patients: increasing efficacy of combined treatment.},
  author={Giacomo Lus and Felice G. Romano and Assunta Scuotto and Catello Accardo and Roberto Cotrufo},
  journal={European neurology},
  year={2004},
  volume={51 1},
  pages={15-20}
}
Current treatments of relapsing-remitting multiple sclerosis (RRMS) with immunosuppressive or immunomodulatory drugs have been shown to modify the course of the disease in a significative number of patients. However, in many cases, the response to either interferon beta (IFN-beta) or azathioprine (AZA) treatments was not satisfactory and new therapeutic approaches are needed. We studied clinical and MRI efficacy, safety and tolerance of AZA and IFN-beta(1a) combined therapy in 23 patients with… CONTINUE READING
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