Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety.

@article{Arnott2003AzathioprineAA,
  title={Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety.},
  author={Ian D. R. Arnott and David Watts and Jack Satsangi},
  journal={Pharmacological research},
  year={2003},
  volume={47 1},
  pages={1-10}
}
Crohn's disease (CD), a chronic relapsing inflammatory condition of the intestines, is a common cause of gastrointestinal morbidity in young people. Although the aetiology of CD is unknown, host, genetic and environmental influences are clearly important. Glucocorticoids remain the mainstay of treatment for active CD, however only two-third of patients will… CONTINUE READING