Axotomy-induced changes in cell structure and membrane excitability are sustained in a vertebrate central neuron.

@article{Faber1981AxotomyinducedCI,
  title={Axotomy-induced changes in cell structure and membrane excitability are sustained in a vertebrate central neuron.},
  author={Donald S. Faber and Steven J. Zottoli},
  journal={Brain research},
  year={1981},
  volume={223 2},
  pages={436-43}
}
The retrograde reactions of the goldfish Mauthner neuron to axotomy 8-10 mm caudal to its soma are detectable within a few weeks and persist for more than 200 days. Morphological changes include chromatolysis, reflecting a redistribution of cytoplasmic ribosomes, and infolding of the nuclear membrane. At the time, the normally inexcitable soma-dendritic membrane becomes capable of impulse initiation; this induced excitability also persists for at least 200 days.