Axotomy accelerates slow component b of axonal transport.

@article{Jacob1991AxotomyAS,
  title={Axotomy accelerates slow component b of axonal transport.},
  author={J{\"u}rgen Jacob and Irvine G. Mcquarrie},
  journal={Journal of neurobiology},
  year={1991},
  volume={22 6},
  pages={
          570-82
        }
}
Because the integrity of an axon depends on the supply of proteins synthesized in the cell body, we examined the effect of axotomy on the transport of structural proteins in rat motor axons, and the effect of altered transport on the rate of outgrowth after a subsequent testing axotomy. To examine the axonal transport of structural proteins, we labeled newly synthesized proteins with 35S-methionine 7 days after a "conditioning" lesion of the sciatic nerve, and removed the nerve 7-21 days later… CONTINUE READING
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