Axonal tau mRNA localization coincides with tau protein in living neuronal cells and depends on axonal targeting signal.

Abstract

Subcellular mRNA localization, a fundamental mechanism for regulating gene expression, leads to local protein translation that results in the generation of neuronal cell polarity. In this study, we have used P19 embryonic carcinoma cells, which are amenable to transfection, and selection of clonal stable cell lines that are not overexpressing the constructs… (More)

Topics

10 Figures and Tables

Cite this paper

@article{Aronov2001AxonalTM, title={Axonal tau mRNA localization coincides with tau protein in living neuronal cells and depends on axonal targeting signal.}, author={Stella Aronov and Gonzalo Aranda and Leah Behar and Irith Ginzburg}, journal={The Journal of neuroscience : the official journal of the Society for Neuroscience}, year={2001}, volume={21 17}, pages={6577-87} }