Axonal site of spike initiation enhances auditory coincidence detection

@article{Kuba2006AxonalSO,
  title={Axonal site of spike initiation enhances auditory coincidence detection},
  author={Hiroshi Kuba and Takahiro Ishii and Harunori Ohmori},
  journal={Nature},
  year={2006},
  volume={444},
  pages={1069-1072}
}
Neurons initiate spikes in the axon initial segment or at the first node in the axon. However, it is not yet understood how the site of spike initiation affects neuronal activity and function. In nucleus laminaris of birds, neurons behave as coincidence detectors for sound source localization and encode interaural time differences (ITDs) separately at each characteristic frequency (CF). Here we show, in nucleus laminaris of the chick, that the site of spike initiation in the axon is arranged at… CONTINUE READING
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