Axonal outgrowth on nano-imprinted patterns.

@article{Johansson2006AxonalOO,
  title={Axonal outgrowth on nano-imprinted patterns.},
  author={Fredrik Johansson and Patrick Carlberg and Nils Danielsen and Lars Montelius and Martin Kanje},
  journal={Biomaterials},
  year={2006},
  volume={27 8},
  pages={1251-8}
}
Nanotechnology has provided methods to fabricate surface patterns with features down to a few nm. If cells or cell processes exhibit contact guidance in response to such small patterns is an interesting question and could be pertinent for many applications. In the present study we investigated if axonal outgrowth was affected by nano-printed patterns in polymethylmethacrylate (PMMA)-covered silicon chips. To this end adult mouse sympathetic and sensory ganglia were mounted in Matrigel on the… CONTINUE READING

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