Axonal mRNAs: functional significance in vertebrates and invertebrates.

  title={Axonal mRNAs: functional significance in vertebrates and invertebrates.},
  author={Evita Mohr and D. F. E. Richter},
  journal={Journal of neurocytology},
  volume={29 11-12},
Sorting of defined mRNA species to distinct cytoplasmic regions is observed throughout the animal kingdom in many cell types, including neurons. During the past years, mRNA localization to dendrites of nerve cells has been characterized in detail. The functional role of these transcripts appears to be obvious: Since dendrites are equipped with the basic translational machinery, certain proteins are likely to be synthesized on-site. Targeting of mRNAs to the axon of vertebrate neurons is less… CONTINUE READING
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