Axonal degeneration/necrosis: a possible ultrastructural marker for Crohn's disease.

@article{Steinhoff1988AxonalDA,
  title={Axonal degeneration/necrosis: a possible ultrastructural marker for Crohn's disease.},
  author={Margaret M. Steinhoff and Ira J. Kodner and Katherine Deschryver-Kecskemeti},
  journal={Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc},
  year={1988},
  volume={1 3},
  pages={
          182-7
        }
}
Axonal degeneration/necrosis has previously been demonstrated in the small bowel autonomic nerve plexus of patients with Crohn's disease. It was suggested that this feature might be helpful in the differential diagnosis of Crohn's disease from other conditions, specifically ulcerative colitis. We performed a blind prospective study and examined tissue from 34 colonic specimens, in 15 patients, by electron microscopy. Cases of Crohn's disease (3 cases), ulcerative colitis (5 cases), and other… CONTINUE READING

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