Axon physiology.

@article{Debanne2011AxonP,
  title={Axon physiology.},
  author={Dominique Debanne and Emilie Campanac and Andrzej Bialowas and Edmond Carlier and Gisèle Alcaraz},
  journal={Physiological reviews},
  year={2011},
  volume={91 2},
  pages={
          555-602
        }
}
Axons are generally considered as reliable transmission cables in which stable propagation occurs once an action potential is generated. Axon dysfunction occupies a central position in many inherited and acquired neurological disorders that affect both peripheral and central neurons. Recent findings suggest that the functional and computational repertoire of the axon is much richer than traditionally thought. Beyond classical axonal propagation, intrinsic voltage-gated ionic currents together… 
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The mechanisms as well as the functional significance of ADP in fine-scale modulation of axonal spike signaling in the CNS, with special reference to hippocampal mossy fibers, one of the best-studied CNS axons, are focused on.
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Kv1 channels located in the axon proper greatly participate in intrinsic excitability of CA3 pyramidal neurons, stressing the importance of the axonal compartment in the regulation of intrinsic neuronal excitability.
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TLDR
It is shown that EAPs and antidromic conduction can occur spontaneously, and after distal axotomy or physiological changes in the axon biochemical environment, and have important implications for the study of neuronal function in vitro, reshaping the understanding on how information flows in neuronal cultures.
Modeling Analysis of Axonal After Potential at Hippocampal Mossy Fibers
TLDR
It is suggested that the capacitive component reflecting passive propagation of upstream action potential substantially contributes to the slow time course of axonal after potential, although voltage-dependent K+ current provided a characteristic voltage dependency of after potential waveform.
Tracking axonal action potential propagation on a high-density microelectrode array across hundreds of sites.
TLDR
Methods to electrically visualize action potential propagation and network topology in cortical neurons grown over custom arrays, which contain 11,011 microelectrodes and are fabricated using complementary metal oxide semiconductor technology are reported.
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Information processing in the axon
TLDR
This review considers recent evidence for the role of intrinsic voltage-gated conductances together with the intrinsic geometrical properties of the axon in the short-term dynamics of neural communication.
Electrogenic Tuning of the Axon Initial Segment
TLDR
In addition to its main role in AP initiation, the new findings suggest that the AIS is also a site of complex AP modulation by specific types of ion channels localized to this axonal domain.
Single‐axon action potentials in the rat hippocampal cortex
TLDR
The observations of propagation reliability to a much longer distance and higher frequency domain than previously reported are extended, and a high safety factor for action potential propagation along thin, varicose axons is suggested.
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