Axon extension and retraction by leech neurons: severing early projections to peripheral targets prevents normal retraction of other projections.


During leech embryogenesis, interactions between homologous neurons in neighboring segments lead to the selective retraction of longitudinal axonal projections by midbody AP and AE neurons, which maintain lateral axonal projections to the periphery. Results of experiments reported here show that disconnecting the lateral projections from the periphery… (More)