Axon degeneration: make the Schwann cell great again

@inproceedings{Wong2017AxonDM,
  title={Axon degeneration: make the Schwann cell great again},
  author={Keit Men Wong and Elisabetta Babetto and Bogdan Beirowski},
  booktitle={Neural regeneration research},
  year={2017}
}
Axonal degeneration is a pivotal feature of many neurodegenerative conditions and substantially accounts for neurological morbidity. A widely used experimental model to study the mechanisms of axonal degeneration is Wallerian degeneration (WD), which occurs after acute axonal injury. In the peripheral nervous system (PNS), WD is characterized by swift dismantling and clearance of injured axons with their myelin sheaths. This is a prerequisite for successful axonal regeneration. In the central… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 83 REFERENCES

Why is Wallerian degeneration in the CNS so slow?

  • Annual review of neuroscience
  • 2007
VIEW 7 EXCERPTS
HIGHLY INFLUENTIAL

Oligodendrocytes contribute to motor neuron death in ALS via SOD1-dependent mechanism.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2016
VIEW 1 EXCERPT
HIGHLY INFLUENTIAL

p38 MAPK activation promotes denervated Schwann cell phenotype and functions as a negative regulator of Schwann cell differentiation and myelination.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2012
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL