Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.

@article{Giuliano2011AxillaryDV,
  title={Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial.},
  author={Armando E. Giuliano and Kelly K Hunt and Karla V. Ballman and Peter D. Beitsch and Pat W Whitworth and Peter W. Blumencranz and A. Marilyn Leitch and Sukamal Saha and Linda Mackie McCall and Monica Morrow},
  journal={JAMA},
  year={2011},
  volume={305 6},
  pages={
          569-75
        }
}
CONTEXT Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of early breast cancer, but it is not clear whether further nodal dissection affects survival. OBJECTIVE To determine the effects of complete axillary lymph node dissection (ALND) on survival of patients with sentinel lymph node (SLN) metastasis of breast cancer. DESIGN, SETTING, AND PATIENTS The American College of Surgeons Oncology Group Z0011 trial, a phase 3 noninferiority trial conducted at 115 sites… CONTINUE READING

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