Avoiding the pitfalls when quantifying thyroid hormones and their metabolites using mass spectrometric methods: The role of quality assurance.

@article{Richards2017AvoidingTP,
  title={Avoiding the pitfalls when quantifying thyroid hormones and their metabolites using mass spectrometric methods: The role of quality assurance.},
  author={Keith H Richards and Eddy Rijntjes and Daniel Rathmann and Josef Koehrle},
  journal={Molecular and cellular endocrinology},
  year={2017},
  volume={458},
  pages={
          44-56
        }
}
This short review aims to assess the application of basic quality assurance (QA) principles in published thyroid hormone bioanalytical methods using mass spectrometry (MS). The use of tandem MS, in particular linked to liquid chromatography has become an essential bioanalytical tool for the thyroid hormone research community. Although basic research laboratories do not usually work within the constraints of a quality management system and regulated environment, all of the reviewed publications… CONTINUE READING