Avidity of IgG antibodies distinguishes primary from non-primary cytomegalovirus infection in pregnant women.

@article{Bodus1998AvidityOI,
  title={Avidity of IgG antibodies distinguishes primary from non-primary cytomegalovirus infection in pregnant women.},
  author={Monique Bod{\'e}us and S Feyder and Patrick Goubau},
  journal={Clinical and diagnostic virology},
  year={1998},
  volume={9 1},
  pages={9-16}
}
BACKGROUND Human cytomegalovirus (HCMV) is the most common cause of viral intrauterine infection. Fetal damage is mostly linked to maternal primary infection. It is therefore important to differentiate primary from non-primary infection in pregnant females. IgM tests often used for this purpose are not reliable enough. OBJECTIVE To evaluate an HCMV-IgG urea-elution assay for its ability to distinguish primary from non-primary infection. In this assay, soaking the antigen-antibody complex with… CONTINUE READING

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