Avian retrovirus DNA internal attachment site requirements for full-site integration in vitro.

@article{Chiu2000AvianRD,
  title={Avian retrovirus DNA internal attachment site requirements for full-site integration in vitro.},
  author={Roger Chiu and Duane P. Grandgenett},
  journal={Journal of virology},
  year={2000},
  volume={74 18},
  pages={8292-8}
}
Concerted integration of retrovirus DNA termini into the host chromosome in vivo requires specific interactions between the cis-acting attachment (att) sites at the viral termini and the viral integrase (IN) in trans. In this study, reconstruction experiments with purified avian myeloblastosis virus (AMV) IN and retrovirus-like donor substrates containing wild-type and mutant termini were performed to map the internal att DNA sequence requirements for concerted integration, here termed full… CONTINUE READING

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