Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy.

@article{Spillner2012AvianIA,
  title={Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy.},
  author={Edzard Spillner and Ingke Braren and Kerstin Greunke and Henning Seismann and Simon Blank and Dion du Plessis},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2012},
  volume={40 5},
  pages={313-22}
}
The generation and use of avian antibodies is of increasing interest in a wide variety of applications within the life sciences. Due to their phylogenetic distance, mechanisms of immune diversification and the way in which they deposit IgY immunoglobulin in the egg yolk, chickens provide a number of advantages compared to mammals as hosts for immunization. These advantages include: the one-step purification of antibodies from egg yolk in large amounts facilitates having a virtually continuous… CONTINUE READING

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